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ForumsMASH / Liver DiseaseMASH resolution without worsening fibrosis — looking for input Page 4

MASH resolution without worsening fibrosis — looking for input

PeptideSynthNJ Wed, Jul 2, 2025 at 8:50 AM 40 replies 1,673 viewsPage 4 of 8
Dr.EndoIndy
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Jul 16, 2025 at 1:42 AM#16
roxy_nash said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Same experience, arrived at from the opposite direction.

42 15mia_MS2, LeilaHI, marcus_mpls and 39 others
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JessicaM_2024
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Jul 17, 2025 at 3:20 PM#17
labquiet_amy said:
Practical: whatever you change, write down the date and the reason.

There is a second half to this that has not been said yet. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

43 16NicoleRaleigh, james_edin, FranDenver and 40 others
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raj_cambridge
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Jul 19, 2025 at 4:58 AM#18

Adding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

44 17TomTeleRx, DoseLogDan, SleepFixSam and 41 others
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carl_compliance
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Jul 20, 2025 at 6:35 PM#19

Following on from labquiet_amy — and this may be the naive question:

Did your prescriber agree with that reading, and if not what was their objection?

45 18FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 42 others
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Admin
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Jul 22, 2025 at 8:11 AM#20

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Carry on.

17 15PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 14 others
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