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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseMASH biomarker panel — looking for input Page 3

MASH biomarker panel — looking for input

tammy_FL Wed, Apr 16, 2025 at 3:46 PM 31 replies 2,203 viewsPage 3 of 7
JakeBK_lifts
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Apr 18, 2025 at 4:35 AM#11
carl_compliance said:
A defensible baseline is short: HbA1c and fasting glucose, a lipid panel with ApoB if you can get it, ALT and AST, creatinine with eGFR, TSH, ferritin…

This answered a question I did not know how to ask. Printing the relevant bit and taking it with me.

3 1TrialTracker_MD, JennaRN, LabKate
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VanRx_Mike
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Apr 19, 2025 at 11:01 AM#12

Adding the clinical framing, because it changes how the question reads.

PSA: get baseline labs BEFORE starting baseline bloodwork therapy. You need a "before" picture to measure progress. My recommended pre-treatment panel:

  1. CMP + A1C + fasting insulin
  2. Complete lipid panel with particle count if possible
  3. hsCRP, ferritin, B12, vitamin D
  4. Thyroid panel (TSH + free T4)
  5. CBC with differential
  6. Liver panel (ALT, AST, GGT)
  7. DEXA scan or body composition

Total cost at Quest without insurance: ~$200. Worth every penny for the data.

4 2MikeNYC_runner and 1 other
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LabKate
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Apr 20, 2025 at 5:28 PM#13
andrew_nyc said:
The liver data is among the strongest non-weight findings in the class.

Shot day Wednesday report relevant to baseline bloodwork:

Week 25. Currently on 2.4mg. Down 21 lbs from starting weight of 233 lbs.

This week's observations: Mild fatigue day 1-2 post-injection, then fine.

Labs due next week — looking forward to seeing the metabolic panel. I'll post results in the Lab Results section when they come in.

Last edited: Apr 20, 2025 at 8:28 PM
5 3Dr.SleepRoch, laura_annarbor, JenMemphis and 2 others
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anders_CPH
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Apr 21, 2025 at 11:55 PM#14
tammy_FL said:
The single most useful discipline is bringing the whole panel to a clinician rather than one flagged value.

Blood work came back perfect. baseline bloodwork + this community = winning. 🏆

Last edited: Apr 22, 2025 at 3:55 AM
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mike_mod
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Apr 23, 2025 at 6:23 AM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. No action needed from anybody.

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