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Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementDiarrhea vs constipation on GLP-1 — need advice Page 8

Diarrhea vs constipation on GLP-1 — need advice

BenResearch_OR Sat, Mar 15, 2025 at 9:12 PM 50 replies 2,016 viewsPage 8 of 10
Dr.SportsMedIN
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Apr 1, 2025 at 8:12 AM#36
anders_CPH said:
It is worth asking what the claim would look like if it were false.

Coming at anders_CPH’s question from a different direction. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

15 13lucas_SP_BR, lisa_labSD, adam_van and 12 others
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kate.chem
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Apr 2, 2025 at 3:22 AM#37

Adding the numbers, since they settle part of this. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

16 14VanRx_Mike, steve_okc, dave_SLC and 13 others
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PeptideSynthNJ
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Apr 2, 2025 at 10:31 PM#38

One thing that is still open after anders_CPH’s answer:

How long did you give it before you decided it was working?

17 15BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 14 others
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Dr.EndoEP
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Apr 3, 2025 at 5:40 PM#39
kate.chem said:
Say what you would expect to see if you were wrong, before you look.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

18 16Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 15 others
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ingrid_STO
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Apr 4, 2025 at 12:48 PM#40
kate.chem said:
Say what you would expect to see if you were wrong, before you look.

Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.

40 13WendyG_ATL, SaraMom3, Dr.MetabolicMD and 37 others
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